CD120a / TNFR1 (30-211, hIgG-His tag)
Specifications
Product Data | |
Species | Human |
Expression Host | Other |
Tag | hIgG-His-tag |
Predicted MW | 47.7 kDa |
Concentration | 0.5 mg/ml (determined by absorbance at 280nm) |
Purity | > 90 % by SDS - PAGE |
Buffer | Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Endotoxin | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Preparation | Liquid purified protein |
Reference Data | |
RefSeq | NP_001056 |
Locus ID | 7132 |
Cytogenetics | 12p13.31 |
Synonyms | CD120a; FPF; MS5; p55; p55-R; p60; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR1-d2; TNFR55 |
Summary | This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by RefSeq, Sep 2016] |
Protein Families | Druggable Genome, Secreted Protein, Transcription Factors, Transmembrane |
Protein Pathways | Adipocytokine signaling pathway, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Cytokine-cytokine receptor interaction, MAPK signaling pathway |
Documents
FAQs |
SDS |
Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TP723427 | Purified recombinant protein of Human tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A). |
USD 230.00 |
|
AR51703PU-S | Recombinant human TNFRSF1A protein, fused to His-tag at N-terminus, was expressed in E.coli. |
USD 320.00 |
|
AR52053PU-S |
USD 320.00 |
||
LC400435 | TNFRSF1A HEK293T cell transient overexpression lysate (as WB positive control) |
USD 95.00 |
|
TP723870 | Purified recombinant protein of Human tumor necrosis factor receptor superfamily, member 1A (sTNF-RI / TNFRSF1A) |
USD 195.00 |
|
AR51703PU-N | Recombinant human TNFRSF1A protein, fused to His-tag at N-terminus, was expressed in E.coli. |
USD 820.00 |
|
AR50554PU-N | Recombinant human TNFRSF1A protein, fused to His-tag at N-terminus, was expressed in E.coli. |
USD 820.00 |
|
LC810243 | TNFRSF1A-knockout Cell lysate from HeLa cell ine, one vial of parental cell line lysate included as control |
USD 495.00 |
|
LC830801 | TNFRSF1A-knockout Cell lysate from HeLa cell line, one vial of parental cell line lysate included as control |
USD 495.00 |
|
LY400435 | Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A) |
USD 315.00 |
|
AR50554PU-S | Recombinant human TNFRSF1A protein, fused to His-tag at N-terminus, was expressed in E.coli. |
USD 320.00 |