FBP1 (1-338, His-tag)

USD 190.00


Availability*
2 Weeks

Size
    • 20 ug


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Specifications

Product Data
Species Human
Expression Host E. coli
Tag His-tag
Predicted MW 39.0 kDa
Concentration 1.0 mg/ml (determined by bradford assay)
Purity > 90 % by SDS - PAGE
Buffer 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol.
Bioactivity Specific activity is > 7,000 pmol/min/ug obtained by measuring the increase of NADPH in absorbance at 340 nm resulting from the reduction of NADP. One unit will oxidize 1.0 pmole of fructose 1,6 diphosphate to fructose 6-phosphate and inorganic phosphate per minute at pH 9.5 at 37C.
Preparation Liquid purified protein
Reference Data
RefSeq NP_000498
Locus ID 2203
Cytogenetics 9q22.32
Synonyms FBP
Summary Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Pentose phosphate pathway

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68 Mouse Clones