Carbonic anhydrase 12 (25-301, His-tag)

CAT#: AR51944PU-S

Recombinant human CA12, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.


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USD 320.00


Availability*
2 Weeks

Size
    • 50 ug


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Specifications

Product Data
Description Recombinant human CA12, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Species Human
Expression Host Other
Expression cDNA Clone or AA Sequence APVNGSKWTY FGPDGENSWS KKYPSCGGLL QSPIDLHSDI LQYDASLTPL EFQGYNLSAN KQFLLTNNGH SVKLNLPSDM HIQGLQSRYS ATQLHLHWGN PNDPHGSEHT VSGQHFAAEL HIVHYNSDLY PDASTASNKS EGLAVLAVLI EMGSFNPSYD KIFSHLQHVK YKGQEAFVPG FNIEELLPER TAEYYRYRGS LTTPPCNPTV LWTVFRNPVQ ISQEQLLALE TALYCTHMDD PSPREMINNF RQVQKFDERL VYTSFSQVQV CTAAGLSHHH HHH
Tag His-tag
Predicted MW 31.94 kDa
Concentration 0.5 mg/ml (determined by absorbance at 280nm)
Purity > 90 % by SDS - PAGE
Buffer Phosphate buffered saline (pH7.4) containing 10% glycerol.
Endotoxin < 1.0 EU per 1 microgram of protein (determined by LAL method)
Preparation Liquid purified protein
Reference Data
RefSeq NP_001209
Locus ID 771
Cytogenetics 15q22.2
Synonyms CA-XII; CAXII; HsT18816; T18816
Summary Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Nitrogen metabolism

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