Interleukin-17A (IL17A) (24-155, His-tag) Human Protein
Interleukin-17A (IL17A) (24-155, His-tag) human recombinant protein, 50 µg
|Description||Interleukin-17A (IL17A) (24-155, His-tag) human recombinant protein, 50 µg|
|Expression cDNA Clone or AA Sequence||GITIPRNPGC PNSEDKNFPR TVMVNLNIHN RNTNTNPKRS SDYYNRSTSP WNLHRNEDPE RYPSVIWEAK CRHLGCINAD GNVDYHMNSV PIQQEILVLR REPPHCPNSF RLEKILVSVG CTCVTPIVHH VAHHHHHH|
|Predicted MW||15.9 kDa|
|Concentration||0.25 mg/ml (determined by bradford assay)|
|Purity||>90% by SDS - PAGE|
|Buffer||Presentation State: Purified
State: Liquid purified protein
Buffer System: Phosphate buffered saline (pH 7.4) containing 20% glycerol, 1mM EDTA, 0.1mM PMSF.
|Endotoxin||< 1.0 Eu per 1 microgram of protein (determined by LAL method)|
|Preparation||Liquid purified protein|
|Protein Description||Recombinant human IL17A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.|
|Storage||Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
|Stability||Shelf life: one year from despatch.|
|Synonyms||CTLA-8; CTLA8; IL-17; IL-17A; IL17|
|Summary||The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]|
|Protein Families||Druggable Genome, Secreted Protein|
|Protein Pathways||Cytokine-cytokine receptor interaction|