PRKAA1 (1-279, His-tag) Human Protein

CAT#: AR51805PU-N

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PRKAA1 (1-279, His-tag) human recombinant protein, 0.5 mg



USD 845.00


Availability*
2 Weeks

Size
    • 500 ug


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Specifications

Product Data
Description PRKAA1 (1-279, His-tag) human recombinant protein, 0.5 mg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MGSSHHHHHH SSGLVPRGSH MGSMRRLSSW RKMATAEKQK HDGRVKIGHY ILGDTLGVGT FGKVKVGKHE LTGHKVAVKI LNRQKIRSLD VVGKIRREIQ NLKLFRHPHI IKLYQVISTP SDIFMVMEYV SGGELFDYIC KNGRLDEKES RRLFQQILSG VDYCHRHMVV HRDLKPENVL LDAHMNAKIA DFGLSNMMSD GEFLRTSCGS PNYAAPEVIS GRLYAGPEVD IWSSGVILYA LLCGTLPFDD DHVPTLFKKI CDGIFYTPQY LNPSVISLLK HMLQVDPMKR ATIKDIREHE WF
Tag His-tag
Predicted MW 34.3 kDa
Concentration 1.0 mg/ml (determined by Bradford assay)
Purity >85% by SDS - PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: Liquid, In 20mM Tris-HCl buffer(pH8.0) containing 10% glycerol.
Preparation Liquid purified protein
Protein Description Recombinant human PRKAA1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_001341957
Locus ID 5562
Cytogenetics 5p13.1
Synonyms AMPK; AMPKa1
Summary The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Adipocytokine signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin signaling pathway, mTOR signaling pathway, Regulation of autophagy

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