MTHFD2 (30-350, His-tag)

CAT#: AR51792PU-N

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Recombinant human MTHFD2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


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USD 845.00


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2 Weeks

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    • 500 ug


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Product Data
Description Recombinant human MTHFD2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Expression Host E. coli
Tag His-tag
Predicted MW 37.2 kDa
Concentration 1.0 mg/ml (determined by Bradford assay)
Purity > 95 % by SDS - PAGE
Buffer Liquid, In Phosphate buffered saline (pH7.4) containing 20% glycerol, 1mM DTT.
Preparation Liquid purified protein
Reference Data
RefSeq NP_006627
Locus ID 10797
Cytogenetics 2p13.1
Synonyms NMDMC
Summary This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009]
Protein Families Druggable Genome
Protein Pathways Glyoxylate and dicarboxylate metabolism, Metabolic pathways, One carbon pool by folate

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68 Mouse Clones