HADHB (34-474, His-tag)
Recombinant human HADHB protein, fused to His-tag at N-terminus, was expressed in E.coli.
Product Datasheet for 'AR51761PU-N'
|Description||Recombinant human HADHB protein, fused to His-tag at N-terminus, was expressed in E.coli.|
|Expression Host||E. coli|
|Predicted MW||49.9 kDa|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Purity||> 90 % by SDS - PAGE|
|Buffer||Liquid, In 20mM phosphate (pH8.0) containing 10% glycerol.|
|Preparation||Liquid purified protein|
|Synonyms||ECHB; MSTP029; MTPB; TP-BETA|
|Summary||This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]|
|Protein Pathways||Fatty acid elongation in mitochondria, Fatty acid metabolism, Metabolic pathways, Valine, leucine and isoleucine degradation|
|LY424879||Transient overexpression lysate of hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit (HADHB), nuclear gene encoding mitochondrial protein||
|AR51761PU-S||Recombinant human HADHB protein, fused to His-tag at N-terminus, was expressed in E.coli.||
|LC424879||HADHB HEK293T cell transient overexpression lysate (as WB positive control)||