HADHB (34-474, His-tag)

CAT#: AR51761PU-N

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Recombinant human HADHB protein, fused to His-tag at N-terminus, was expressed in E.coli.


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USD 845.00


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2 Weeks

Size
    • 500 ug


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Specifications

Product Data
Description Recombinant human HADHB protein, fused to His-tag at N-terminus, was expressed in E.coli.
Species Human
Expression Host E. coli
Tag His-tag
Predicted MW 49.9 kDa
Concentration 0.5 mg/ml (determined by Bradford assay)
Purity > 90 % by SDS - PAGE
Buffer Liquid, In 20mM phosphate (pH8.0) containing 10% glycerol.
Preparation Liquid purified protein
Reference Data
RefSeq NP_000174
Locus ID 3032
Cytogenetics 2p23.3
Synonyms ECHB; MSTP029; MTPB; TP-BETA
Summary This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
Protein Pathways Fatty acid elongation in mitochondria, Fatty acid metabolism, Metabolic pathways, Valine, leucine and isoleucine degradation

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68 Mouse Clones