Interleukin-33 (IL33) (109-266, His-tag) Mouse Protein

CAT#: AR51680PU-S

Interleukin-33 (IL33) (109-266, His-tag) mouse recombinant protein, 50 µg

Product Images

Specifications

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MGSSHHHHHH SSGLVPRGSH MGSSIQGTSL LTQSPASLST YNDQSVSFVL ENGCYVINVD DSGKDQEQDQ VLLRYYESPC PASQSGDGVD GKKLMVNMSP IKDTDIWLHA NDKDYSVELQ RGDVSPPEQA FFVLHKKSSD FVSFECKNLP GTYIGVKDNQ LALVEEKDES CNNIMFKLSK I
• Tag: His-tag
• Predicted MW: 18.1 kDa
• Concentration: lot specific
• Purity: >90% by SDS - PAGE
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Liquid purified protein
  Buffer System: Phosphate buffered saline, 10% glycerol, 1 mM DTT
• Endotoxin: < 1.0 EU per 1 μg of protein (determined by LAL method)
• Preparation: Liquid purified protein
• Protein Description: Recombinant mouse IL33 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Storage: Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
  Avoid repeated freezing and thawing.
  
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_001158196
• Locus ID: 77125
• UniProt ID: Q8BVZ5
• Cytogenetics: 19 C1
• Synonyms: 9230117N10Rik; Il-33; Il1f11; NF-HEV
• Summary: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury.[UniProtKB/Swiss-Prot Function]