Platelet factor 4 / PF4 (32-101, His-tag) Human Protein

CAT#: AR50929PU-S

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Platelet factor 4 / PF4 (32-101, His-tag) human recombinant protein, 20 µg



USD 330.00


Availability*
2 Weeks

Size
    • 20 ug


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Specifications

Product Data
Description Platelet factor 4 / PF4 (32-101, His-tag) human recombinant protein, 20 µg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MGSSHHHHHH SSGLVPRGSH MEAEEDGDLQ CLCVKTTSQV RPRHITSLEV IKAGPHCPTA QLIATLKNGR KICLDLQAPL YKKIIKKLLE S
Tag His-tag
Predicted MW 10.0 kDa
Concentration 0.25 mg/ml (determined by Bradford assay)
Purity >85% by SDS - PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
Preparation Liquid purified protein
Protein Description Recombinant human CXCL4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_002610
Locus ID 5196
Cytogenetics 4q13.3
Synonyms CXCL4; PF-4; SCYB4
Summary This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction

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