BMP6 (375-513, His-tag)

CAT#: AR50914PU-S

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Recombinant human BMP6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


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USD 320.00


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2 Weeks

Size
    • 20 ug


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Specifications

Product Data
Description Recombinant human BMP6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Expression Host E. coli
Tag His-tag
Predicted MW 18 kDa
Concentration 0.25 mg/ml (determined by Bradford assay)
Purity > 85 % by SDS - PAGE
Buffer 10 mM Sodium citrate buffer (pH 3.5) containing 10% glycerol.
Preparation Liquid purified protein
Reference Data
RefSeq NP_001709
Locus ID 654
Cytogenetics 6p24.3
Synonyms VGR; VGR1
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway
Protein Pathways Hedgehog signaling pathway, TGF-beta signaling pathway

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68 Mouse Clones