CD106 / VCAM1 (25-698, His-tag) Human Protein

CAT#: AR50397PU-N

CD106 / VCAM1 (25-698, His-tag) human recombinant protein, 0.25 mg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MGSSHHHHHH SSGLVPRGSH MFKIETTPES RYLAQIGDSV SLTCSTTGCE SPFFSWRTQI DSPLNGKVTN EGTTSTLTMN PVSFGNEHSY LCTATCESRK LEKGIQVEIY SFPKDPEIHL SGPLEAGKPI TVKCSVADVY PFDRLEIDLL KGDHLMKSQE FLEDADRKSL ETKSLEVTFT PVIEDIGKVL VCRAKLHIDE MDSVPTVRQA VKELQVYISP KNTVISVNPS TKLQEGGSVT MTCSSEGLPA PEIFWSKKLD NGNLQHLSGN ATLTLIAMRM EDSGIYVCEG VNLIGKNRKE VELIVQEKPF TVEISPGPRI AAQIGDSVML TCSVMGCESP SFSWRTQIDS PLSGKVRSEG TNSTLTLSPV SFENEHSYLC TVTCGHKKLE KGIQVELYSF PRDPEIEMSG GLVNGSSVTV SCKVPSVYPL DRLEIELLKG ETILENIEFL EDTDMKSLEN KSLEMTFIPT IEDTGKALVC QAKLHIDDME FEPKQRQSTQ TLYVNVAPRD TTVLVSPSSI LEEGSSVNMT CLSQGFPAPK ILWSRQLPNG ELQPLSENAT LTLISTKMED SGVYLCEGIN QAGRSRKEVE LIIQVTPKDI KLTAFPSESV KEGDTVIISC TCGNVPETWI ILKKKAETGD TVLKSIDGAY TIRKAQLKDA GVYECESKNK VGSQLRSLTL DVQGRENNKD YFSPE
• Tag: His-tag
• Predicted MW: 767.9 kDa
• Concentration: lot specific
• Purity: >80% by SDS - PAGE
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Liquid purified protein
  Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
• Preparation: Liquid purified protein
• Protein Description: Recombinant human VCAM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Storage: Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
  Avoid repeated freezing and thawing.
  
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_001069
• Locus ID: 7412
• UniProt ID: P19320
• Cytogenetics: 1p21.2
• Synonyms: CD106; INCAM-100
• Summary: This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration