Tumor necrosis factor (TNF-alpha) (80-235)

CAT#: AR50300PU-S

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Recombinant mouse TNFa protein was expressed in E.coli and purified by using conventional chromatography.


 Product Datasheet for 'AR50300PU-S'

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USD 320.00


Availability*
2 Weeks

Size
    • 100 ug


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Specifications

Product Data
Description Recombinant mouse TNFa protein was expressed in E.coli and purified by using conventional chromatography.
Species Mouse
Expression Host E. coli
Predicted MW 17.4 kDa
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 95 % by SDS - PAGE
Buffer Phosphate buffered saline (pH 7.4)
Preparation Liquid purified protein
Reference Data
RefSeq NP_001265530
Locus ID 21926
Cytogenetics 17 18.59 cM
Synonyms DIF; TNF-a; TNF-alpha; Tnfa; TNFalpha; Tnfsf1a; TNFSF2; Tnlg1f
Summary This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. Members of this family are classified based on primary sequence, function, and structure. This protein is synthesized as a type-II transmembrane protein and is reported to be cleaved into products that exert distinct biological functions. It plays an important role in the innate immune response as well as regulating homeostasis but is also implicated in diseases of chronic inflammation. In mouse deficiency of this gene is associated with defects in response to bacterial infection, with defects in forming organized follicular dendritic cell networks and germinal centers, and with a lack of primary B cell follicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

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68 Mouse Clones