NFKBIB / IKBB (1-356, His-tag)

CAT#: AR50253PU-S

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Recombinant human NFKBIB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.


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USD 330.00


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2 Weeks

Size
    • 100 ug


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Product Data
Description Recombinant human NFKBIB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Species Human
Expression Host E. coli
Tag His-tag
Predicted MW 40.3 kDa
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 90 % by SDS - PAGE
Buffer 20 mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
Preparation Liquid purified protein
Reference Data
RefSeq NP_001230045
Locus ID 4793
Cytogenetics 19q13.2
Synonyms IKBB; TRIP9
Summary The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
Protein Families Stem cell - Pluripotency, Transcription Factors
Protein Pathways Adipocytokine signaling pathway, B cell receptor signaling pathway, Chemokine signaling pathway, Cytosolic DNA-sensing pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway

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68 Mouse Clones