Thiamine pyrophosphokinase 1 (TPK1) (1-243, His-tag) Human Protein

CAT#: AR50240PU-N

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Recombinant human TPK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.


Product Datasheet for 'AR50240PU-N'


USD 845.00


Availability*
2 Weeks

Size
    • 500 ug


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Specifications

Product Data
Description Recombinant human TPK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MGSSHHHHHH SSGLVPRGSH MGSHMEHAFT PLEPLLSTGN LKYCLVILNQ PLDNYFRHLW NKALLRACAD GGANRLYDIT EGERESFLPE FINGDFDSIR PEVREYYATK GCELISTPDQ DHTDFTKCLK MLQKKIEEKD LKVDVIVTLG GLAGRFDQIM ASVNTLFQAT HITPFPIIII QEESLIYLLQ PGKHRLHVDT GMEGDWCGLI PVGQPCMQVT TTGLKWNLTN DVLAFGTLVS TSNTYDGSGV VTVETDHPLL WTMAIKS
Tag His-tag
Predicted MW 29.8 kDa
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 90 % by SDS - PAGE
Buffer 20 mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
Preparation Liquid purified protein
Reference Data
RefSeq NP_001035947
Locus ID 27010
Cytogenetics 7q35
Synonyms HTPK1; PP20; THMD5
Summary The protein encoded by this gene functions as a homodimer and catalyzes the conversion of thiamine to thiamine pyrophosphate, a cofactor for some enzymes of the glycolytic and energy production pathways. Defects in this gene are a cause of thiamine metabolism dysfunction syndrome-5. [provided by RefSeq, Apr 2017]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Thiamine metabolism

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68 Mouse Clones
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