Complement C8G (21-202, His-tag)

CAT#: AR50060PU-S

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Recombinant human C8G protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


Product Datasheet for 'AR50060PU-S'


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USD 330.00


Availability*
2 Weeks

Size
    • 100 ug


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Product Data
Description Recombinant human C8G protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Expression Host E. coli
Tag His-tag
Predicted MW 22.6 kDa
Concentration 0.5 mg/ml (determined by Bradford)
Purity > 95 % by SDS - PAGE
Buffer 20 mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.15M NaCl.
Preparation Liquid purified protein
Reference Data
RefSeq NP_000597
Locus ID 733
Cytogenetics 9q34.3
Synonyms C8C
Summary The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity. [provided by RefSeq, Jul 2011]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus

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68 Mouse Clones