SUFU / SUFUH (1-484, His-tag)

CAT#: AR50046PU-N

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Recombinant human SUFU protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


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USD 845.00


Availability*
2 Weeks

Size
    • 500 ug


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Specifications

Product Data
Description Recombinant human SUFU protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Expression Host E. coli
Tag His-tag
Predicted MW 56.1 kDa
Concentration 0.5mg/ml (determined by Bradford assay)
Purity > 90 % by SDS - PAGE
Buffer 20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 50mM NaCl
Preparation Liquid purified protein
Reference Data
RefSeq NP_001171604
Locus ID 51684
Cytogenetics 10q24.32
Synonyms JBTS32; PRO1280; SUFUH; SUFUXL
Summary The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer

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68 Mouse Clones