CXCL1 / GRO-alpha (35-107, His-tag)

USD 620.00


Availability*
2 Weeks

Size
    • 500 ug


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Specifications

Product Data
Species Human
Expression Host E. coli
Tag His-tag
Predicted MW 10.1 kDa
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 90 % by SDS - PAGE
Buffer 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Endotoxin < 1.0 EU per 1 microgram of protein (determined by LAL method)
Preparation Liquid purified protein
Reference Data
RefSeq NP_001502
Locus ID 2919
Cytogenetics 4q13.3
Synonyms FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1
Summary This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway

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68 Mouse Clones