VEGFR-1 / Flt-1 (D1-7) (Fc Chimera)

CAT#: AR31149PU-N

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Recombinant Mouse soluble Vascular Endothelial Growth Factor Receptor-1 (sVEGFR-1(D7) was fused with the Fc part of human IgG1. The recombinant mature sVEGFR-1(D7)/Fc is a disulfide-linked homodimeric protein. The sVEGFR-1(D7)/Fc monomers have a mass of approximately 130 kDa. The soluble receptor protein consists of all 7 extracellular domains (Tyr23-Asn757), which contain all the information necessary for high affinity ligand binding.
Result by N-terminal sequencing: SGSKLKD


 Product Datasheet for 'AR31149PU-N'

USD 300.00


Availability*
2 Weeks

Size
    • 50 ug


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Product Data
Description Recombinant Mouse soluble Vascular Endothelial Growth Factor Receptor-1 (sVEGFR-1(D7) was fused with the Fc part of human IgG1. The recombinant mature sVEGFR-1(D7)/Fc is a disulfide-linked homodimeric protein. The sVEGFR-1(D7)/Fc monomers have a mass of approximately 130 kDa. The soluble receptor protein consists of all 7 extracellular domains (Tyr23-Asn757), which contain all the information necessary for high affinity ligand binding.
Result by N-terminal sequencing: SGSKLKD
Species Mouse
Expression Host Insect
Predicted MW 130 kDa
Purity > 95 % by SDS-PAGE and visualised by silver stain
Buffer PBS, pH 7.4 without stabilizers
Bioactivity The activity of sVEGFR-1/Fc was determined by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells.
The ED50 for this effect is typically 10-30 ng/ml.
Reconstitution Restore in water or medium to a concentration not lower than 50 µg/ml.
The lyophilised sVEGFR-1/Fc is soluble in water and most aqueous buffers.
Preparation Lyophilized purified protein
Reference Data
RefSeq NP_034358
Locus ID 14254
Synonyms AI323757; Flt-1; sFlt1; VEGFR-1; VEGFR1

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68 Mouse Clones