CD70 Human Protein

CAT#: AR31047PU-S

CD70 human recombinant protein, 10 µg

Specifications

Product Data

• Species: Human
• Expression Host: CHO
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  HHHHHHHHPS PGGSGGQRFA QAQQQLPLES LGWDVAELQL NHTGPQQDPR LYWQGGPALG RSFLHGPELD KGQLRIHRDG IYMVHIQVTL AICSSTTASR HHPTTLAVGI CSPASRSISL LRLSFHQGCT IASQRLTPLA RGDTLCTNLT GTLLPSRNTD ETFFGVQWVR P
• Predicted MW: 18.8 kDa
• Purity: >95% by SDS-PAGE gel and HPLC analyses
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Lyophylized purified protein
• Bioactivity: Biological: Determined by its ability to stimulate human IL-8 production by Human PBMC using a concentration range of 10.0-25.0 ng/ml.
  Note: Results may vary with PBMC donors.
• Endotoxin: < 0.1 ng per μg (1EU/μg)
• Reconstitution: Restore in water to a concentration of 0.1-1.0 mg/ml.
  Do Not Vortex.
  This solution can then be diluted into other aqueous buffers and stored at 2-8°C for one week or (with a carrier protein, e.g. 0.1% BSA)) at -20°C to -80°C for longer.
• Preparation: Lyophylized purified protein
• Protein Description: Recombinant Human sCD27L contains the extracellular domain plus an N-terminal His-Tag.
  The calculated molecular weight of Recombinant Human sCD27L is 18.8 kDa.
• Note: Centrifuge vial before opening.
• Storage: Store the lyophilized protein at -20°C.
  Following reconstitution product is stable for 3 months when stored in working aliquots with a carrier protein at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.

Reference Data

• RefSeq: NP_001243
• Locus ID: 970
• UniProt ID: P32970, A0A0U5JA32
• Cytogenetics: 19p13.3
• Synonyms: CD27-L; CD27L; CD27LG; LPFS3; TNFSF7; TNLG8A
• Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
• Protein Families: ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction