MIP4 / CCL18 (22-89, His-tag) Human Protein

CAT#: AR09793PU-S

MIP4 / CCL18 (22-89, His-tag) human recombinant protein, 10 µg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MGSSHHHHHH SSGLVPRGSH MGSHMQVGTN KELCCLVYTS WQIPQKFIVD YSETSPQCPK PGVILLTKRG RQICADPNKK WVQKYISDLK LNA
• Tag: His-tag
• Predicted MW: 10.4 kDa
• Concentration: lot specific
• Purity: >95%
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Liquid purified peptide
  Buffer System: 10 mM Sodium Citrate pH 3.5, 10% Glycerol
• Endotoxin: < 1.0 EU per 1 μg of protein (determined by LAL method )
• Preparation: Liquid purified peptide
• Protein Description: Recombinant human CCL18, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_002979
• Locus ID: 6362
• UniProt ID: P55774
• Cytogenetics: 17q12
• Synonyms: AMAC-1; AMAC1; CKb7; DC-CK1; DCCK1; MIP-4; PARC; SCYA18
• Summary: This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq, Sep 2014]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction