PPAR-gamma (209-477, His-tag)

CAT#: AR09574PU-N

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Recombinant human PPARG protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


 Product Datasheet for 'AR09574PU-N'

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USD 330.00


Availability*
2 Weeks

Size
    • 100 ug


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Product Data
Description Recombinant human PPARG protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Expression Host E. coli
Tag His-tag
Concentration 1.0 mg/ml (determined by Bradford assay)
Purity > 95 % by SDS - PAGE
Buffer 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1 M NaCl
Preparation Liquid purified protein
Reference Data
RefSeq NP_001317544
Locus ID 5468
Cytogenetics 3p25.2
Synonyms CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma
Summary This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Huntington's disease, Pathways in cancer, PPAR signaling pathway, Thyroid cancer

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68 Mouse Clones