Arginase-1 (1-322, His-tag) Human Protein

CAT#: AR09474PU-N

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Arginase-1 (1-322, His-tag) human recombinant protein, 0.1 mg



USD 300.00


Availability*
2 Weeks

Size
    • 100 ug


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Specifications

Product Data
Description Arginase-1 (1-322, His-tag) human recombinant protein, 0.1 mg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MSAKSRTIGI IGAPFSKGQP RGGVEEGPTV LRKAGLLEKL KEQECDVKDY GDLPFADIPN DSPFQIVKNP RSVGKASEQL AGKVAEVKKN GRISLVLGGD HSLAIGSISG HARVHPDLGV IWVDAHTDIN TPLTTTSGNL HGQPVSFLLK ELKGKIPDVP GFSWVTPCIS AKDIVYIGLR DVDPGEHYIL KTLGIKYFSM TEVDRLGIGK VMEETLSYLL GRKKRPIHLS FDVDGLDPSF TPATGTPVVG GLTYREGLYI TEEIYKTGLL SGLDIMEVNP SLGKTPEEVT RTVNTAVAIT LACFGLAREG NHKPIDYLNP PKLEHHHHHH
Tag His-tag
Predicted MW 35.8 kDa
Concentration 0.5 mg/ml (determined by Bradford assay)
Purity >85% by SDS - PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 2 mM DTT, 100 mM NaCl
Preparation Liquid purified protein
Protein Description Recombinant human ARG1, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_000036
Locus ID 383
Cytogenetics 6q23.2
Synonyms arginase, liver; arginase 1; liver-type arginase; OTTHUMP00000017209; type I arginase
Summary Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Protein Families Druggable Genome
Protein Pathways Arginine and proline metabolism, Metabolic pathways

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