HADH / HCDH (13-314, His-tag)

CAT#: AR09400PU-L

Recombinant HADH protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques.


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USD 720.00


Availability*
2 Weeks

Size
    • 0.5 mg


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Specifications

Product Data
Description Recombinant HADH protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MGSSHHHHHH SSGLVPRGSH MSSSSTASAS AKKIIVKHVT VIGGGLMGAG IAQVAAATGH TVVLVDQTED ILAKSKKGIE ESLRKVAKKK FAENPKAGDE FVEKTLSTIA TSTDAASVVH STDLVVEAIV ENLKVKNELF KRLDKFAAEH TIFASNTSSL QITSIANATT RQDRFAGLHF FNPVPVMKLV EVIKTPMTSQ KTFESLVDFS KALGKHPVSC KDTPGFIVNR LLVPYLMEAI RLYERGDASK EDIDTAMKLG AGYPMGPFEL LDYVGLDTTK FIVDGWHEMD AENPLHQPSP SLNKLVAENK FGKKTGEGFY KYK
Tag His-tag
Predicted MW 35.1 kDa
Concentration 1.0 mg/ml (determined by Bradford assay)
Purity > 95 % by SDS-PAGE
Buffer 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 M NaCl
Preparation Liquid purified protein
Reference Data
RefSeq NP_001171634
Locus ID 3033
Cytogenetics 4q25
Synonyms HAD; HADH1; HADHSC; HCDH; HHF4; MSCHAD; SCHAD
Summary This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15. [provided by RefSeq, May 2010]
Protein Pathways Butanoate metabolism, Fatty acid elongation in mitochondria, Fatty acid metabolism, leucine and isoleucine degradation, Lysine degradation, Metabolic pathways, Tryptophan metabolism, Valine

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