TARC / CCL17 (24-94, His-tag) Human Protein

CAT#: AR09248PU-L

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TARC / CCL17 (24-94, His-tag) human protein, 0.25 mg


Product Datasheet for 'AR09248PU-L'


USD 845.00


Availability*
2 Weeks

Size
    • 250 ug


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Specifications

Product Data
Description TARC / CCL17 (24-94, His-tag) human protein, 0.25 mg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MGSSHHHHHH SSGLVPRGSH MARGTNVGRE CCLEYFKGAI PLRKLKTWYQ TSEDCSRDAI VFVTVQGRAI CSDPNNKRVK NAVKYLQSLE RS
Tag His-tag
Predicted MW 10.3 kDa
Concentration 0.5 mg/ml (determined by Bradford assay)
Purity >95% by SDS - PAGE
Buffer Presentation State: Purified
State: Liquid purified peptide
Buffer System: PBS, pH 7.4, containing 10% glycerol
Endotoxin < 1.0 EU per 1 µg of protein (determined by LAL method )
Preparation Liquid purified peptide
Protein Description CCL17, fused to His-tag, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_002978
Locus ID 6361
Cytogenetics 16q21
Synonyms A-152E5.3; ABCD-2; SCYA17; TARC
Summary This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction

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