RAC2 (1-189, His-tag) Human Protein

CAT#: AR09246PU-L

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RAC2 (1-189, His-tag) human recombinant protein, 0.5 mg


Product Datasheet for 'AR09246PU-L'


USD 845.00


Availability*
2 Weeks

Size
    • 500 ug


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Specifications

Product Data
Description RAC2 (1-189, His-tag) human recombinant protein, 0.5 mg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MGSSHHHHHH SSGLVPRGSH MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE VRHHCPSTPI ILVGTKLDLR DDKDTIEKLK EKKLAPITYP QGLALAKEID SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ PTRQQKRAC
Tag His-tag
Predicted MW 23.3 kDa
Concentration 1.0 mg/ml (determined by Bradford assay)
Purity >95% by SDS - PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 2 mM EDTA, 2 mM DTT, 0.1 M NaCl
Preparation Liquid purified protein
Protein Description Recombinant human RAC2, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_002863
Locus ID 5880
Cytogenetics 22q13.1
Synonyms EN-7; Gx; HSPC022; p21-Rac2
Summary This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]
Protein Families Druggable Genome
Protein Pathways Adherens junction, Axon guidance, B cell receptor signaling pathway, Chemokine signaling pathway, Colorectal cancer, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Pancreatic cancer, Pathways in cancer, Regulation of actin cytoskeleton, VEGF signaling pathway, Viral myocarditis, Wnt signaling pathway

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