Protein phosphatase 1G / PPM1G (317-546, His-tag) Human Protein

CAT#: AR09071PU-L

Protein phosphatase 1G / PPM1G (317-546, His-tag) human recombinant protein, 0.5 mg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MGSSHHHHHH SSGLVPRGSH MEGKEEPGSD SGTTAVVALI RGKQLIVANA GDSRCVVSEA GKALDMSYDH KPEDEVELAR IKNAGGKVTM DGRVNGGLNL SRAIGDHFYK RNKNLPPEEQ MISALPDIKV LTLTDDHEFM VIACDGIWNV MSSQEVVDFI QSKISQRDEN GELRLLSSIV EELLDQCLAP DTSGDGTGCD NMTCIIICFK PRNTAELQPE SGKRKLEEVL STEGAEENGN SDKKKKAKRD
• Tag: His-tag
• Predicted MW: 27 kDa
• Concentration: lot specific
• Purity: >95% by SDS PAGE
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Liquid purified protein
  Buffer System: 25 mM Tris pH 7.5, 1 mM DTT, 1 mM EDTA, 2 mM β-mercaptoethanol, 20% glycerol
• Preparation: Liquid purified protein
• Protein Description: Recombinant human PPM1G, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography techniques.
• Storage: Store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_817092
• Locus ID: 5496
• UniProt ID: O15355, Q6IAU5
• Cytogenetics: 2p23.3
• Synonyms: PP2CG; PP2CGAMMA; PPP2CG
• Summary: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]
• Protein Families: Druggable Genome, Phosphatase