Interleukin-6 / IL6

CAT#: AR05234PU-S

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His-tagged recombinant interleukin-6 expressed in E.coli. Thsi protein induces corticosterone secretion in vivo and induces proliferation of the IL-6 dependant murine hybridoma cell line 7TD1 in vitro.


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USD 485.00


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5 Days

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    • 50 ug


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Product Data
Description His-tagged recombinant interleukin-6 expressed in E.coli. Thsi protein induces corticosterone secretion in vivo and induces proliferation of the IL-6 dependant murine hybridoma cell line 7TD1 in vitro.
Species Human
Expression Host Other
Concentration 0,5 mg/ml
Purity >85% by Ni Chelate chromatography
Buffer Phosphate buffered saline
Preparation Liquid purified protein
Reference Data
RefSeq NP_000591
Locus ID 3569
Cytogenetics 7p15.3
Synonyms BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6
Summary This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Jak-STAT signaling pathway, NOD-like receptor signaling pathway, Pathways in cancer, Prion diseases, Toll-like receptor signaling pathway

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68 Mouse Clones