Heat shock protein 70 / HSP70 (active) Human Protein

CAT#: AR03022PU-N

Heat shock protein 70 / HSP70 (active) human recombinant protein, 0.1 mg

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Concentration: lot specific
• Purity: >95% pure as determined by SDS-PAGE analysis
• Presentation: Aff - Purified
• Buffer: Presentation State: Aff - Purified
  State: Liquid protein
  Buffer System: 20 mM Tris, 50 mM KCl, 5 mM MgCl2, 1 mM DTT, pH 7.5
• Preparation: Liquid protein
• Applications: ATPase Assay, WB control, Binding Assays, ELISA reference standard, Lipid Interaction Assays, Chaperone assays.
• Protein Description: Recombinant Human Hsp70 Protein, cloned from a human cDNA library, with ATPase activity, native sequence, no tags
• Storage: Store the antigen (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.

Reference Data

• RefSeq: NP_005336
• Locus ID: 3303
• UniProt ID: P08107, P0DMV8, P0DMV9, A8K5I0, B3KTT5
• Cytogenetics: 6p21.33
• Synonyms: HEL-S-103; HSP70-1; HSP70-1A; HSP70-2; HSP70.1; HSP70.2; HSP70I; HSP72; HSPA1
• Summary: This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
• Protein Pathways: Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Prion diseases, Spliceosome