HSPA8 / HSC70 (active) Human Protein
HSPA8 / HSC70 (active) human recombinant protein, 2x0.1 mg
|Description||HSPA8 / HSC70 (active) human recombinant protein, 2x0.1 mg|
|Expression Host||E. coli|
|Purity||>90% pure as determined by SDS-PAGE analysis.|
|Buffer||Presentation State: Aff - Purified
State: Liquid affinity purified protein
Buffer System: Na-Phosphate, pH 7.5 (20 mM), 150 mM NaCl, 10% Glycerol, 200 mM Imidazole.
|Preparation||Liquid affinity purified protein|
|Applications||ATPase Assay, WB control, Binding Assays, ELISA reference standard.
This protein has ATPase activity at the time of manufacture of 3.2 uM phosphate liberated/hr/ug protein in a 200 uL reaction at 37 C (pH 7.5) in the presence of 20 uL of 1 mM ATP using a Malachite Green assay.
|Protein Description||Recombinant Human Hsc70 Protein with ATPase activity, his-tagged|
|Storage||Store the antibody (in aliquots) at -20°C.
Can be shipped at 2-8 °C.
Avoid repeated freezing and thawing.
|Stability||Shelf life: One year from despatch.|
|Synonyms||HEL-33; HEL-S-72p; HSC54; HSC70; HSC71; HSP71; HSP73; HSPA10; LAP-1; LAP1; NIP71|
|Summary||This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]|
|Protein Families||Stem cell - Pluripotency|
|Protein Pathways||Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Spliceosome|