Heat shock protein 70 / HSP70 (active) Human Protein

CAT#: AR03018PU-N

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Recombinant Human Hsp70 Protein with ATPase activity, his-tagged, cloned from a Human cDNA library

Product Datasheet for 'AR03018PU-N'

USD 455.00

5 Days

    • 100 ug

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Product Data
Description Recombinant Human Hsp70 Protein with ATPase activity, his-tagged, cloned from a Human cDNA library
Species Human
Expression Host E. coli
Concentration 3 mg/ml (Lot specific)
Purity > 90 % pure as determined by SDS-PAGE analysis.
Buffer Sodium Phosphate, pH 7.5 (20 mM), 150 mM NaCl, 10% Glycerol, 200 mM Imidazole.
Bioactivity The protein has ATPase activity at the time of manufacture of 3.3 µM phosphate liberated/hr/µg protein in a 200 µl reaction at 37°C (pH7.5) in the presence of 20 µl of 1mM ATP using a Malachite Green assay.
Preparation Liquid affinity purified protein.
Reference Data
RefSeq NP_005336
Locus ID 3303
Cytogenetics 6p21.33
Synonyms HEL-S-103; HSP70-1; HSP70-1A; HSP70-2; HSP70.1; HSP70.2; HSP70I; HSP72; HSPA1
Summary This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
Protein Pathways Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Prion diseases, Spliceosome


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