HSP90AA1 / HSP90 alpha
Recombinant Hsp90 alpha cloned from a Human cDNA library
Product Datasheet for 'AR03017PU-S'
|Description||Recombinant Hsp90 alpha cloned from a Human cDNA library|
|Purity||> 90 % pure as determined by SDS-PAGE analysis (Purified by Multy-step Chromatography).|
|Buffer||50mM Tris pH 7.5, 5mM Bme, 0.3M NaCl, 10% Glycerol.|
|Synonyms||EL52; HSP86; Hsp89; HSP89A; Hsp90; HSP90A; HSP90N; HSPC1; HSPCA; HSPCAL1; HSPCAL4; HSPN; LAP-2; LAP2|
|Summary||The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]|
|Protein Families||Druggable Genome|
|Protein Pathways||Antigen processing and presentation, NOD-like receptor signaling pathway, Progesterone-mediated oocyte maturation, Pathways in cancer, Prostate cancer|
|The use of this Proteins has been cited in the following citations:|
Coexposure to mercury increases immunotoxicity of trichloroethylene.
,Gilbert KM, Rowley B, Gomez-Acevedo H, Blossom SJ,
Toxicol. Sci. 2018
,PubMed ID 21084432
The rapid and direct determination of ATPase activity by ion exchange chromatography and the application to the activity of heat shock protein-90.
,Bartolini M, Wainer IW, Bertucci C, Andrisano V,
J Pharm Biomed Anal 2018
,PubMed ID 22497853
Targeting the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation.
,Goode KM, Petrov DP, Vickman RE, Crist SA, Pascuzzi PE, Ratliff TL, Davisson VJ, Hazbun TR,
Biochim. Biophys. Acta 2017
,PubMed ID 28495207
Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients.
,Saito Y, Akazawa-Ogawa Y, Matsumura A, Saigoh K, Itoh S, Sutou K, Kobayashi M, Mita Y, Shichiri M, Hisahara S, Hara Y, Fujimura H, Takamatsu H, Hagihara Y, Yoshida Y, Hamakubo T, Kusunoki S, Shimohama S, Noguchi N,
Sci Rep 2016
,PubMed ID 27470541
Experimental Anti-Inflammatory Drug Semapimod Inhibits TLR Signaling by Targeting the TLR Chaperone gp96.
,Wang J, Grishin AV, Ford HR,
J. Immunol. 2016
,PubMed ID 27194788
Identification of new FGF1 binding partners-Implications for its intracellular function.
,Bober J, Olsnes S, Kostas M, Bogacz M, Zakrzewska M, Otlewski J,
IUBMB Life 2016
,PubMed ID 26840910
Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp.
,Rateb ME, Houssen WE, Arnold M, Abdelrahman MH, Deng H, Harrison WT, Okoro CK, Asenjo JA, Andrews BA, Ferguson G, Bull AT, Goodfellow M, Ebel R, Jaspars M,
J. Nat. Prod. 2011
,PubMed ID 21553813
|AR03017PU-N||Recombinant Hsp90 alpha cloned from a Human cDNA library||
|TP312496||Recombinant protein of human heat shock protein 90kDa alpha (cytosolic), class A member 1 (HSP90AA1), transcript variant 2||
|SA6029X||Recombinant Human Hsp90 alpha, fused to His-tag at N-terminus, was cloned into an E. coli expression vector and was purified to apparent homogeneity by using conventional column chromatography techniques.||
|AR03017PU-L||Recombinant Hsp90 alpha cloned from a Human cDNA library||
|PH312496||HSP90AA1 MS Standard C13 and N15-labeled recombinant protein (NP_005339)||
|SA6029||Recombinant Human Hsp90 alpha, fused to His-tag at N-terminus, was cloned into an E. coli expression vector and was purified to apparent homogeneity by using conventional column chromatography techniques.||
|PH318420||HSP90AA1 MS Standard C13 and N15-labeled recombinant protein (NP_001017963)||
|TP318420||Recombinant protein of human heat shock protein 90kDa alpha (cytosolic), class A member 1 (HSP90AA1), transcript variant 1||
|LC417365||HSP90AA1 HEK293T cell transient overexpression lysate (as WB positive control)||
|LY400399||Transient overexpression lysate of heat shock protein 90kDa alpha (cytosolic), class A member 1 (HSP90AA1), transcript variant 1||
|LY417365||Transient overexpression lysate of heat shock protein 90kDa alpha (cytosolic), class A member 1 (HSP90AA1), transcript variant 2||
|LC400399||HSP90AA1 HEK293T cell transient overexpression lysate (as WB positive control)||