SPG21 (NM_001127889) Human Mass Spec Standard

CAT#: PH325431

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SPG21 MS Standard C13 and N15-labeled recombinant protein (NP_001121361)

  View other "SPG21" proteins (9)

USD 2,712.00

3 Weeks

    • 10 ug

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Product Data
Description SPG21 MS Standard C13 and N15-labeled recombinant protein (NP_001121361)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225431
Predicted MW 35 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001121361
RefSeq Size 1658
RefSeq ORF 924
Synonyms ABHD21; ACP33; BM-019; GL010; MAST
Locus ID 51324
UniProt ID Q9NZD8, A0A024R5Y1
Cytogenetics 15q22.31
Summary The protein encoded by this gene binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. Mutations in this gene are associated with autosomal recessive spastic paraplegia 21 (SPG21), also known as mast syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]


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