AKR1D1 (NM_005989) Human Mass Spec Standard

CAT#: PH323056

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AKR1D1 MS Standard C13 and N15-labeled recombinant protein (NP_005980)



  View other "AKR1D1" proteins (7)

USD 2,712.00


Availability*
3 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description AKR1D1 MS Standard C13 and N15-labeled recombinant protein (NP_005980)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC223056
Predicted MW 37.2 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_005980
RefSeq Size 2692
RefSeq ORF 978
Synonyms 3o5bred; CBAS2; SRD5B1
Locus ID 6718
UniProt ID P51857
Cytogenetics 7q33
Summary The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010]
Protein Families Druggable Genome
Protein Pathways Androgen and estrogen metabolism, C21-Steroid hormone metabolism, Metabolic pathways, Primary bile acid biosynthesis

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