ZAK(ZAK) (NM_016653) Human Mass Spec Standard

CAT#: PH321970

ZAK MS Standard C13 and N15-labeled recombinant protein (NP_057737)

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USD 1,995.00


Availability*
3 Weeks

Size
    • 10 ug

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Specifications

Product Data
Description ZAK MS Standard C13 and N15-labeled recombinant protein (NP_057737)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221970
Predicted MW 91 kDa
Protein Sequence
Tag C-MYC/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_057737
RefSeq Size 3767
RefSeq ORF 2400
Synonyms AZK; MLK7; mlklak; MLT; MLTK; MRK; pk
Locus ID 51776
Cytogenetics 2q31.1
Summary This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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