Junctional Adhesion Molecule 1(F11R) (NM_016946) Human Mass Spec Standard

CAT#: PH321478

F11R MS Standard C13 and N15-labeled recombinant protein (NP_058642)

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USD 1,995.00


Availability*
3 Weeks

Size
    • 10 ug

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Specifications

Product Data
Description F11R MS Standard C13 and N15-labeled recombinant protein (NP_058642)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221478
Predicted MW 32.58 kDa
Protein Sequence
Tag C-MYC/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_058642
RefSeq Size 3660
RefSeq ORF 897
Synonyms CD321; JAM; JAM1; JAMA; JCAM; KAT; PAM-1
Locus ID 50848
Cytogenetics 1q23.3
Summary Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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