Tapasin(TAPBP) (NM_003190) Human Mass Spec Standard

CAT#: PH317968

TAPBP MS Standard C13 and N15-labeled recombinant protein (NP_003181)

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USD 1,995.00


Availability*
3 Weeks

Size
    • 10 ug

Product images

Specifications

Product Data
Description TAPBP MS Standard C13 and N15-labeled recombinant protein (NP_003181)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217968
Predicted MW 47.63 kDa
Protein Sequence
Tag C-MYC/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_003181
RefSeq Size 3629
RefSeq ORF 1344
Synonyms NGS17; TAPA; TPN; TPSN
Locus ID 6892
Cytogenetics 6p21.32
Summary This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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