JAK3 (NM_000215) Human Mass Spec Standard

CAT#: PH317928

JAK3 MS Standard C13 and N15-labeled recombinant protein (NP_000206)

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USD 1,995


Availability*
3 Weeks

Size
    • 10 ug

Product images

Specifications

Product Data
Description JAK3 MS Standard C13 and N15-labeled recombinant protein (NP_000206)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217928
Predicted MW 124.9 kDa
Protein Sequence
Tag C-MYC/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_000206
RefSeq Size 4025
RefSeq ORF 3372
Synonyms JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK
Locus ID 3718
Cytogenetics 19p13.11
Summary The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
Protein Pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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