FTS (AKTIP) (NM_022476) Human Mass Spec Standard

CAT#: PH315277

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AKTIP MS Standard C13 and N15-labeled recombinant protein (NP_071921)

  View other "AKTIP" proteins (5)

USD 2,712.00

3 Weeks

    • 10 ug

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Product Data
Description AKTIP MS Standard C13 and N15-labeled recombinant protein (NP_071921)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC215277
Predicted MW 33.2 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_071921
RefSeq Size 2193
RefSeq ORF 879
Synonyms FT1; FTS
Locus ID 64400
UniProt ID Q9H8T0, A0A024R6T5
Cytogenetics 16q12.2
Summary The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]


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