GLUT4 (SLC2A4) (NM_001042) Human Mass Spec Standard

CAT#: PH313717

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SLC2A4 MS Standard C13 and N15-labeled recombinant protein (NP_001033)

  View other "SLC2A4" proteins (3)

USD 2,260.00

3 Weeks

    • 10 ug

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Product Data
Description SLC2A4 MS Standard C13 and N15-labeled recombinant protein (NP_001033)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213717
Predicted MW 54.6 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001033
RefSeq Size 2128
RefSeq ORF 1527
Synonyms GLUT4
Locus ID 6517
UniProt ID P14672
Cytogenetics 17p13.1
Summary This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Adipocytokine signaling pathway, Insulin signaling pathway, Type II diabetes mellitus


Other Versions

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Customer Reviews 
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