CTBP2 (NM_001083914) Human Mass Spec Standard

CAT#: PH313339

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CTBP2 MS Standard C13 and N15-labeled recombinant protein (NP_001077383)

  View other "CTBP2" proteins (7)

USD 2,055.00

3 Weeks

    • 10 ug

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Product Data
Description CTBP2 MS Standard C13 and N15-labeled recombinant protein (NP_001077383)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213339
Predicted MW 48.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001077383
RefSeq Size 3441
RefSeq ORF 1335
Synonyms C-terminal binding protein 2; OTTHUMP00000020699; OTTHUMP00000020701; ribeye
Locus ID 1488
Cytogenetics 10q26.13
Summary This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
Protein Families Stem cell - Pluripotency, Stem cell relevant signaling - Wnt Signaling pathway
Protein Pathways Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway


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Customer Reviews 
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