UBE2C (NM_181802) Human Mass Spec Standard

CAT#: PH312704

UBE2C MS Standard C13 and N15-labeled recombinant protein (NP_861518)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description UBE2C MS Standard C13 and N15-labeled recombinant protein (NP_861518)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence [RC212704]
Predicted MW 15.6 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_861518
RefSeq Size 1490
RefSeq ORF 423
Synonyms dJ447F3.2; UBCH10
Locus ID 11065
Cytogenetics 20q13.12
Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19. [provided by RefSeq, Aug 2013].
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