Serotonin transporter (SLC6A4) (NM_001045) Human Mass Spec Standard

CAT#: PH310187

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SLC6A4 MS Standard C13 and N15-labeled recombinant protein (NP_001036)



  View other "SLC6A4" proteins (3)

USD 2,260.00


Availability*
3 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description SLC6A4 MS Standard C13 and N15-labeled recombinant protein (NP_001036)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210187
Predicted MW 70.1 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001036
RefSeq Size 2756
RefSeq ORF 1890
Synonyms 5-HTT; 5-HTTLPR; 5HTT; hSERT; HTT; OCD1; SERT; SERT1
Locus ID 6532
UniProt ID P31645, B2R7Y7
Cytogenetics 17q11.2
Summary This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake. There have been conflicting results in the literature about the possible effect, if any, that this polymorphism may play in behavior and depression. [provided by RefSeq, May 2019]
Protein Families Druggable Genome, Transmembrane

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Other Versions

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