LAIR1 (NM_002287) Human Mass Spec Standard

CAT#: PH306439

LAIR1 MS Standard C13 and N15-labeled recombinant protein (NP_002278)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description LAIR1 MS Standard C13 and N15-labeled recombinant protein (NP_002278)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206439
Predicted MW 31.2 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_002278
RefSeq Size 2816
RefSeq ORF 861
Synonyms CD305; LAIR-1
Locus ID 3903
Cytogenetics 19q13.42
Summary The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.