P4HA1 (NM_001017962) Human Mass Spec Standard

CAT#: PH306055

P4HA1 MS Standard C13 and N15-labeled recombinant protein (NP_001017962)

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USD 1,995

3 Weeks

    • 10 ug

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Product Data
Description P4HA1 MS Standard C13 and N15-labeled recombinant protein (NP_001017962)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206055
Predicted MW 61.05 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001017962
RefSeq Size 2752
RefSeq ORF 1602
Synonyms P4HA; P4HA
Locus ID 5033
Cytogenetics 10q22.1
Summary This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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