DAZL (NM_001351) Human Mass Spec Standard

CAT#: PH305328

DAZL MS Standard C13 and N15-labeled recombinant protein (NP_001342)

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USD 1,995


Availability*
3 Weeks

Size
    • 10 ug

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Specifications

Product Data
Description DAZL MS Standard C13 and N15-labeled recombinant protein (NP_001342)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC205328
Predicted MW 33 kDa
Protein Sequence
Tag C-MYC/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001342
RefSeq Size 3056
RefSeq ORF 885
Synonyms DAZH; DAZL1; DAZLA; SPGYLA
Locus ID 1618
Cytogenetics 3p24.3
Summary The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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