Ku70(XRCC6) (NM_001469) Human Mass Spec Standard

CAT#: PH304048

XRCC6 MS Standard C13 and N15-labeled recombinant protein (NP_001460)

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USD 1,995.00


Availability*
3 Weeks

Size
    • 10 ug

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Specifications

Product Data
Description XRCC6 MS Standard C13 and N15-labeled recombinant protein (NP_001460)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204048
Predicted MW 69.7 kDa
Protein Sequence
Tag C-MYC/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001460
RefSeq Size 2156
RefSeq ORF 1827
Synonyms CTC75; CTCBF; G22P1; KU70; ML8; TLAA
Locus ID 2547
Cytogenetics 22q13.2
Summary The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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