Ube1L(UBA7) (NM_003335) Human Mass Spec Standard

CAT#: PH302883

UBA7 MS Standard C13 and N15-labeled recombinant protein (NP_003326)

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USD 1,995.00


Availability*
3 Weeks

Size
    • 10 ug

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Specifications

Product Data
Description UBA7 MS Standard C13 and N15-labeled recombinant protein (NP_003326)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202883
Predicted MW 111.5 kDa
Protein Sequence
Tag C-MYC/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_003326
RefSeq Size 3330
RefSeq ORF 3036
Synonyms D8; UBA1B; UBE1L; UBE2
Locus ID 7318
Cytogenetics 3p21.31
Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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