PAFAH1B3 (NM_002573) Human Mass Spec Standard

CAT#: PH301268

PAFAH1B3 MS Standard C13 and N15-labeled recombinant protein (NP_002564)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description PAFAH1B3 MS Standard C13 and N15-labeled recombinant protein (NP_002564)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201268
Predicted MW 25.6 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_002564
RefSeq Size 1021
RefSeq ORF 693
Locus ID 5050
Cytogenetics 19q13.2
Summary This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009].
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