PLCG 2 (PLCG2) (NM_002661) Human Mass Spec Standard

CAT#: PH300442

Reviews ()
Write a review

PLCG2 MS Standard C13 and N15-labeled recombinant protein (NP_002652)



  View other "PLCG2" proteins (3)

USD 2,055.00


Availability*
3 Weeks

Size
    • 10 ug


Product images

Specifications

Product Data
Description PLCG2 MS Standard C13 and N15-labeled recombinant protein (NP_002652)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200442
Predicted MW 147.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_002652
RefSeq Size 8707
RefSeq ORF 3795
Synonyms APLAID; FCAS3; PLC-gamma-2; PLC-IV
Locus ID 5336
Cytogenetics 16q23.3
Summary The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
Protein Families Druggable Genome
Protein Pathways B cell receptor signaling pathway, Calcium signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Glioma, Inositol phosphate metabolism, Leukocyte transendothelial migration, Metabolic pathways, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pathways in cancer, Phosphatidylinositol signaling system, VEGF signaling pathway, Vibrio cholerae infection

Documents

Other Versions

Other products for "PLCG2"
Frequently bought together (2)
Transient overexpression lysate of phospholipase C, gamma 2 (phosphatidylinositol-specific) (PLCG2)
    • 100 ug

USD 325.00


Anti-PLCG2 (Phospho-Tyr753) Rabbit Polyclonal Antibody
    • 100 ul

USD 345.00

Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
68 Mouse Clones
Molbio tools