ZAK(ZAK) (NM_133646) Human Mass Spec Standard

CAT#: PH300069

ZAK MS Standard C13 and N15-labeled recombinant protein (NP_598407)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description ZAK MS Standard C13 and N15-labeled recombinant protein (NP_598407)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200069
Predicted MW 51.4 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_598407
RefSeq Size 7194
RefSeq ORF 1365
Synonyms AZK; MLK7; mlklak; MLT; MLTK; MRK; pk; SFMMP
Locus ID 51776
Cytogenetics 2q31.1
Summary This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Protein Pathways
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